Vagustim V2 device

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Clinical & scientific research

Scientific hardware for your clinical trials.

Scientifically-backed. Parameter-level control. Research-ready.

Vagustim V2 Plus is a non-invasive auricular vagus nerve stimulation device for investigators who need to specify a stimulation protocol, hold it constant across a cohort, and report exactly what was delivered. If you are designing a human study, or a preclinical one, we would like to hear about it.

Vagustim V2 Plus device
  • 50+ scientific studies
  • Parameter-level control
  • Session data export
  • FCC and CE certified
Why V2 Plus in a study

One device, every variable under control.

Most consumer devices ship with preset programmes and hidden parameters. V2 Plus was built the other way round: placement, parameters and current are adjustable, sessions can be followed and controlled remotely, and everything that was delivered can be exported.

  • 01Bilateral or unilateral

    Both ears, left only or right only, from the same device.

  • 02Adjustable parameters

    Frequency, pulse width, duty cycle and session duration.

  • 03Adjustable current

    Intensity set per participant and recorded with each session.

  • 04Remote monitoring

    Follow sessions and adherence, including take-home arms.

  • 05Remote control

    Assign and adjust parameter profiles from a distance.

  • 06Data export

    Session logs exported for analysis and supplements.

01 · CONFIGURE

Every parameter, including the current

Frequency, pulse width, duty cycle, session duration and current intensity are set directly. The protocol in your methods section is the protocol that is delivered, and another lab can reproduce it afterwards.

02 · PLACE & ASSIGN

Bilateral or unilateral, per participant

Each profile defines placement (both ears, left only or right only) along with its parameter set. Active and control arms run on identical hardware, and delivery stays constant across a cohort and across sites.

03 · MONITOR & EXPORT

Remote monitoring, remote control, full export

Follow sessions as they happen, adjust profiles remotely, and export every session with its parameters, current and duration. Adherence and dose become measured variables, not assumptions.

Vagustim V2 Plus · Research configuration

What you can control, and what gets written down.

The V2 Plus is the model used in research settings. It exposes the stimulation parameters directly and supports bilateral or unilateral auricular placement, so active and control conditions can be defined within a single device.

ParameterRangeNotes for study design
Frequency1 to 1000 HzCovers the low frequency range used in most published non-invasive auricular vagus nerve stimulation protocols, with headroom for parameter sweep designs.
Pulse widthAdjustableSet independently of frequency, so charge per pulse can be held constant while frequency varies.
Duty cycleAdjustable on / offSupports intermittent trains as well as continuous stimulation.
Session durationAdjustableTypical published sessions run 15 to 30 minutes. The limit is set by your protocol, not by the device.
IntensityParticipant titratedCommonly titrated to perceptual threshold and below pain threshold. On-device controls allow adjustment without the app.
PlacementBilateral or unilateralAdjustable earsets for the tragus and cymba conchae, sized across ear morphologies. Left only, right only and bilateral arms are all achievable.
Remote accessMonitoring and controlSessions and adherence followed remotely, with parameter profiles assigned and adjusted without a site visit.
Session loggingPer-session exportParameters, duration and history recorded per participant profile, then exported for analysis.
OperationOffline capableOn-device controls work without a phone. That matters for scanner environments and take-home arms.

Full electrical specifications, waveform characteristics and conformity documentation are supplied on request for ethics submissions and institutional procurement review.

Control conditions

Sham design is the hardest part. We will work on it with you.

Sham design for non-invasive auricular vagus nerve stimulation has no settled standard. Earlobe placement, sub-threshold intensity, brief ramp and stop, and no-stimulation controls each trade internal validity against blinding integrity, and the choice shapes what your result can claim. Electrode placement during sham is itself an open methodological question, one our team has published on.