Vagustim V2 device

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Research collaborations

Research-grade control, in a wearable device.

Scientifically-backed. Parameter-level control. Research-ready.

Vagustim makes auricular vagus activation hardware for research teams who need to specify a protocol, hold it constant across a cohort, and report exactly what was delivered. If you are designing a study, we would like to hear about it.

Vagustim V2 Plus device
  • 60+ scientific studies
  • Parameter-level control
  • Session data export
  • FCC and CE certified
Why V2 Plus in a study

One device, every variable under control.

Most consumer devices ship with preset programmes and hidden parameters. V2 Plus was built the other way round: placement, parameters and current are adjustable, sessions can be followed and controlled remotely, and everything that was delivered can be exported.

  • 01Bilateral or unilateral

    Both ears, left only or right only, from the same device.

  • 02Adjustable parameters

    Frequency, pulse width, duty cycle and session duration.

  • 03Adjustable current

    Intensity set per participant and recorded with each session.

  • 04Remote monitoring

    Follow sessions and adherence, including take-home arms.

  • 05Remote control

    Assign and adjust parameter profiles from a distance.

  • 06Data export

    Session logs exported for analysis and supplements.

01 · CONFIGURE

Every parameter, including the current

Frequency, pulse width, duty cycle, session duration and current intensity are set directly. The protocol in your methods section is the protocol that is delivered, and another lab can reproduce it afterwards.

02 · PLACE & ASSIGN

Bilateral or unilateral, per participant

Each profile defines placement (both ears, left only or right only) along with its parameter set. Active and control arms run on identical hardware, and delivery stays constant across a cohort and across sites.

03 · MONITOR & EXPORT

Remote monitoring, remote control, full export

Follow sessions as they happen, adjust profiles remotely, and export every session with its parameters, current and duration. Adherence and dose become measured variables, not assumptions.

Vagustim V2 Plus · Research configuration

What you can control, and what gets written down.

The V2 Plus is the model used in research settings. It exposes the activation parameters directly and supports bilateral or unilateral auricular placement, so active and control conditions can be defined within a single device.

ParameterRangeNotes for study design
Frequency1 to 1000 HzCovers the low frequency range used in most published auricular vagus activation protocols, with headroom for parameter sweep designs.
Pulse widthAdjustableSet independently of frequency, so charge per pulse can be held constant while frequency varies.
Duty cycleAdjustable on / offSupports intermittent trains as well as continuous activation.
Session durationAdjustableTypical published sessions run 15 to 30 minutes. The limit is set by your protocol, not by the device.
IntensityParticipant titratedCommonly titrated to perceptual threshold and below pain threshold. On-device controls allow adjustment without the app.
PlacementBilateral or unilateralAdjustable earsets for the tragus and cymba conchae, sized across ear morphologies. Left only, right only and bilateral arms are all achievable.
Remote accessMonitoring and controlSessions and adherence followed remotely, with parameter profiles assigned and adjusted without a site visit.
Session loggingPer-session exportParameters, duration and history recorded per participant profile, then exported for analysis.
OperationOffline capableOn-device controls work without a phone. That matters for scanner environments and take-home arms.

Full electrical specifications, waveform characteristics and conformity documentation are supplied on request for ethics submissions and institutional procurement review.

Control conditions

Sham design is the hardest part. We will work on it with you.

Sham design for auricular vagus activation has no settled standard. Earlobe placement, sub-threshold intensity, brief ramp and stop, and no-activation controls each trade internal validity against blinding integrity, and the choice shapes what your result can claim. Electrode placement during sham is itself an open methodological question, one our team has published on.

Grounded in evidence

The world’s most studied bilateral vagus activation device

Backed by 60+ scientific studies and used in research across leading universities and institutes.

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Reported outcomes

Selected results from 60+ scientific studies

Each figure is an outcome reported in a single study population using Vagustim for auricular vagus activation. These are not pooled or meta-analytic effects: designs, sample sizes, comparators and parameters differ between studies.

+55% Vagal activity Increase
+47% Pain threshold Increase
+40% Memory performance Improvement
+41% Sleep quality Enhancement
37% Fatigue Reduction
28% Mental strain Decrease
+23% Parasympathetic activity Enhancement
+16% Taste and smell Improvement
+15% Social cognition Improvement
+15% Probabilistic learning Enhancement
+13% Brain activity Increase
+6% Agility Improvement
6% Muscle tension Decrease
+4% Weight control Improvement

Results in specific study populations. Individual results may vary. Request the full study library below to read the source papers.

Terms of collaboration

What a collaboration involves, stated plainly.

We are a device manufacturer with a commercial interest in this field. Being explicit about that at the start is better for your study and for our credibility, so here is the exchange.

What we provide
  1. Devices at research pricing

    Quoted per study and invoiced to the institution, with quantities matched to your arms and an attrition allowance.

  2. Parameter consultation

    On frequency, pulse width, duty cycle and placement, drawing on protocols already used in published work.

  3. Technical documentation

    For ethics submissions and procurement: specifications, conformity records and safety information.

  4. Data export support

    So session logs reach your analysis pipeline in a usable form.

  5. Replacement units and consumables

    For the duration of data collection, so a hardware fault does not cost you a participant.

What we ask
  1. Scientific independence stays with you

    We do not review results before submission, and we do not ask for approval over what you publish.

  2. Pre-registration

    Of the protocol and primary outcome, where the design allows it.

  3. Disclosure of our support

    In the funding or conflict of interest statement, in whatever form your journal requires.

  4. A copy of the published paper

    So we can list it and learn from it.

  5. Authorship only where it is earned

    If our engineers contribute intellectually, that is a conversation. If they do not, they are acknowledged, not listed.

From first message to first participant

How it proceeds.

Four steps, each with a named person on our side. Most studies move from inquiry to shipped units within a few weeks of ethics approval.

  1. STEP 01You send the inquiry

    The form below. A paragraph on the question you are asking is worth more to us than a completed spec sheet.

  2. STEP 02A scientific call, not a sales call

    Thirty minutes with someone who knows the hardware and the literature. We will tell you if auricular vagus activation is the wrong tool for your question.

  3. STEP 03Protocol and quotation

    A written parameter set for your arms, plus a quotation and the documentation your ethics committee and procurement office will ask for.

  4. STEP 04Devices, training, then we step back

    Units configured and shipped, a session with your research staff, and a named contact for the duration of data collection.

Collaboration inquiry

Tell us about the study.

Everything here helps us answer usefully rather than generically. If a field does not apply yet, leave it. An early stage idea is a fine reason to write.

  • The question you are trying to answer, and the primary outcome
  • Population or model, planned sample size and devices needed

Every inquiry is answered by a named person, usually within five working days. Prefer email? Write to sales@vagustim.io.

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Research collaborationsStart an inquiry